There has been a resurgence of interest in understanding how metabolic pathways are altered in cancer and how these alterations can be exploited for therapeutic gain. Many of the signaling pathways that drive tumorigenesis directly regulate metabolic pathways that support cell growth. Increasingly, metabolites themselves are recognized to play important roles regulating tumor initiation and progression. Beyond providing the building blocks for cell proliferation, metabolites can directly influence stress response pathways, chromatin modifications and gene expression that collectively drive tumor development. This meeting will bring experts together to discuss the intersection between cancer cell signaling and metabolism and explore how cancer cells exploit cellular signaling and metabolic pathways to support malignant growth.

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